Juvelook Under Eye Singapore

What Juvelook is and how PDLLA works under the eyes

Juvelook is supplied as a powder that is reconstituted with saline before injection. Each vial contains 42.5 mg of PDLLA microspheres and 7.5 mg of non-cross-linked HA. The HA binds water and produces an immediate hydrating effect, but because it is not cross-linked, it is broken down within days and contributes hydration rather than lasting volume. The PDLLA particles provoke a controlled inflammatory response in which fibroblasts, the cells that produce collagen, deposit new collagen around the particles as they are gradually absorbed, thickening the dermis and adding a small amount of volume.

• Injection Small amounts are placed beneath the lower lid with a blunt cannula or a fine needle. About 0.4 ml per eye was used at each session in the Singapore-led study.
• Juvelook Volume is a different product Juvelook Volume (Lenisna) contains 170 mg of PDLLA and 30 mg of HA, four times the PDLLA and HA content of Juvelook, and is designed to restore deeper volume elsewhere on the face. A quote should therefore specify which of the two products is used.
• Singapore registration Vaim Juvelook is listed on the Health Sciences Authority (HSA) Medical Device Register (DE0507634) for filling skin depressions and restoring soft-tissue volume. Use under the eyes rests on the injector’s clinical judgement.
• Other names Some clinics list Juvelook only as a PDLLA skin booster without naming the brand.

Juvelook results in under-eye studies

• EvidenceEvidence for the tear trough and lower-lid skin, Grade C. In a Singapore-led prospective study, 15 women received three Juvelook sessions of about 0.4 ml per eye. Investigator and patient ratings of the tear trough improved after each session. Lower-lid elasticity, hydration, skin quality and radiance also improved, and no adverse events were reported. Without a control group, the size of the effect attributable to Juvelook cannot be established, and both authors have received speaker fees from the manufacturer.
• Longer follow-up, Grade C A Korean case series of women with tear trough deformity reported that the improvement was maintained at 6 months. A 2025 case report documented the collagen response on ultrasound imaging.
• Randomised evidence, other areas The only randomised trial of a Juvelook product compared Juvelook Volume with poly-L-lactic acid (PLLA), the active ingredient of Sculptra, in the nasolabial folds of 33 people and found it non-inferior, meaning no worse within a predefined margin, at 24 weeks. No randomised trial has tested Juvelook under the eyes.
• Juvelook vs Rejuran, Grade D No human study has compared the two products directly.

Juvelook price in Singapore (2026)

Prices are compiled from published Singapore clinic price lists, and some exclude goods and services tax (GST). Because some clinics quote Juvelook per vial and others per syringe or per session, prices are comparable only when a quote states the product, the volume injected and the number of sessions.

Juvelook side effects and nodule risk

• Common Swelling, tenderness and bruising at the injection sites.
• Nodules Firm lumps can appear weeks after injection, usually where the particles have been placed too superficially in the thin lower-lid skin, because the lid has too little overlying tissue to conceal the collagen that forms around them. In one published case, tear-trough nodules that appeared three weeks after Juvelook resolved within 24 hours of monopolar radiofrequency treatment. In another, lower-eyelid granulomas that developed after three PDLLA sessions with a sharp needle required two operations.
• Not dissolvable Hyaluronidase, the enzyme used to dissolve hyaluronic acid filler, breaks down the HA component of Juvelook but not the PDLLA particles, so a lump cannot be reversed by injection in the way a filler lump can.
• Vessel blockage and vision loss A Singapore case report describes vision loss and multiple strokes after PDLLA was injected into the nasolabial folds and under the eyes, a complication that arises when product enters an artery and travels to the vessels that supply the eye and brain. A 2026 review of biostimulator injectables found one reported case of visual loss after PDLLA-HA. Although the event is rare, under-eye injection should be performed by a doctor trained to recognise and treat it.

Frequently asked questions about Juvelook under the eyes

General information, not medical advice. A registered medical practitioner should be consulted before any treatment. Dark Eye Circles Singapore does not sell treatments.